Comparison of self-hosted inference orchestrators: vLLM, LocalAI, exo, and GPUStack
September 20, 2026
A technical survey of OpenAI-compatible orchestrators evaluates multi-machine support, cache-aware routing, and deployment platforms. vLLM offers prefix caching and production-ready Kubernetes support, while Ollama provides the widest OS compatibility but lacks multi-machine orchestration.
HOW THIS AFFECTS YOU
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builderUse this to select the correct orchestration layer based on your need for multi-GPU scaling versus local OS compatibility.